A property (of an object) is opaque to an observer when he or she cannot deduce the property from its set of observations. If each observer is attached to a given set of properties (the so-called secrets), then the system is said to be opaque if each secret is opaque to the corresponding observer. Opacity has been studied in the context of discrete event dynamic systems where technique of control theory were designed to enforce opacity. To the best of our knowledge, this paper is the first attempt to formalize opacity of artifacts in data-centric workflow systems. We motivate this problem and give some assumptions that guarantee the decidability of opacity. Some techniques for enforcing opacity are indicated.