Jean-Luc Gouzé ; Valérie Lemesle - Two simple growth models in the chemostat

arima:1895 - Revue Africaine de Recherche en Informatique et Mathématiques Appliquées, September 2, 2008, Volume 9, 2007 Conference in Honor of Claude Lobry, 2008 - https://doi.org/10.46298/arima.1895
Two simple growth models in the chemostatArticle

Authors: Jean-Luc Gouzé ORCID1; Valérie Lemesle 1

  • 1 Modeling and control of renewable resources

[en]
In a chemostat, transient oscillations are often experimentally observed during cell growth. The aim of this paper is to propose simple autonomous models which are able (or not) to generate these oscillations, and to investigate them analytically. Our point of view is based on a simplification of the cell cycle in which there are two states (mature and immature) with the transfer between the two dependent on the available resources. We built two similar models, one with cell biomass and the other with cell number density. We prove that the first one oscillates, but not the second. This paper is dedicated to Claude Lobry, who helped us to build a first version of these models.

[fr]
On observe parfois des oscillations pendant la croissance de cellules dans un chémostat. Nous proposons ici deux modèles autonomes simples de croissance cellulaire (en dimension trois) basés sur des hypothèses réalistes, structurés en stades (les cellules matures et les cellules immatures) : le premier modèle est écrit en nombre de cellules, et peut présenter des oscillations. Le deuxième modèle est écrit en biomasse, et n’admet pas d’oscillations à cause de la conservation de la masse. Nous étudions les deux modèles. Cet article est dédié à Claude Lobry, qui a participé aux premières étapes de l’écriture des modèles.


Volume: Volume 9, 2007 Conference in Honor of Claude Lobry, 2008
Published on: September 2, 2008
Imported on: February 18, 2008
Keywords: [INFO]Computer Science [cs], [MATH]Mathematics [math], [en] chemostat, cell growth, oscillations; [fr] hémostat, croissance cellulaire, oscillations

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